References

  1. World Health Organisation. The top 10 causes of death. 2017 January 2017 [cited 2017 13/03/17]; Factsheet].
  2. Murray, C.J., et al., Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The lancet, 2013. 380(9859): p. 2197-2223.
  3. McKevitt, C., et al., Self-reported long-term needs after stroke. Stroke, 2011. 42(5): p. 1398-1403.
  4. Wolfe, C.D., et al., Estimates of outcomes up to ten years after stroke: analysis from the prospective South London Stroke Register. PLoS Med, 2011. 8(5): p. e1001033.
  5. Feigin, V.L., et al., Atlas of the Global Burden of Stroke (1990-2013): The GBD 2013 Study. Neuroepidemiology, 2015. 45(3): p. 230-6.
  6. Grieve, R., et al., A Comparison of the Costs and Survival of Hospital-Admitted Stroke Patients Across Europe. Stroke, 2001. 32(7): p. 1684-1691.
  7. Matchar, D.B., et al., International Comparison of Poststroke Resource Use: A Longitudinal Analysis in Europe. Journal of Stroke and Cerebrovascular Diseases, 2015. 24(10): p. 2256-2262.
  8. Cadilhac, D.A., et al., National stroke registries for monitoring and improving the quality of hospital care: A systematic review. International Journal of Stroke, 2016. 11(1): p. 28-40.
  9. King’s College London, Stroke clinician/researcher responses to KCL questionnaire. 2016.
  10. Heuschmann, P.U., et al., Incidence of stroke in Europe at the beginning of the 21st century. Stroke, 2009. 40(5): p. 1557-63.
  11. Appelros, P., et al., High incidence rates of stroke in Orebro, Sweden: Further support for regional incidence differences within Scandinavia. Cerebrovasc Dis, 2002. 14(3-4): p. 161-8.
  12. Pikija, S., et al., A population-based prospective 24-month study of stroke: incidence and 30-day case-fatality rates of first-ever strokes in Croatia. Neuroepidemiology, 2012. 38(3): p. 164-71.
  13. Correia, M., et al., Changes in stroke incidence, outcome, and associated factors in Porto between 1998 and 2011. Int J Stroke, 2016.
  14. Vibo, R., J. Korv, and M. Roose, One-year outcome after first-ever stroke according to stroke subtype, severity, risk factors and pre-stroke treatment. A population-based study from Tartu, Estonia. Eur J Neurol, 2007. 14(4): p. 435-9.
  15. Correia, M., et al., Prospective Community-Based Study of Stroke in Northern Portugal: Incidence and Case Fatality in Rural and Urban Populations. Stroke, 2004. 35(9): p. 2048-2053.
  16. Hilmarsson, A., O. Kjartansson, and E. Olafsson, Incidence of first stroke: a population study in Iceland. Stroke, 2013. 44(6): p. 1714-6.
  17. Rothwell, P.M., et al., Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). Lancet, 2005. 366(9499): p. 1773-83.
  18. Musolino, R., et al., First-ever stroke incidence and 30-day case fatality in the Sicilian Aeolian archipelago, Italy. Stroke, 2005. 36(12): p. 2738-41.
  19. Manobianca, G., et al., Low incidence of stroke in southern Italy: a population-based study. Stroke, 2008. 39(11): p. 2923-8.
  20. Wang, Y., A.G. Rudd, and C.D. Wolfe, Age and ethnic disparities in incidence of stroke over time: the South London Stroke Register. Stroke, 2013. 44(12): p. 3298-304.
  21. Diaz-Guzman, J., et al., Stroke and transient ischemic attack incidence rate in Spain: the IBERICTUS study. Cerebrovasc Dis, 2012. 34(4): p. 272-81.
  22. Palm, F., et al., Stroke Incidence and Survival in Ludwigshafen am Rhein, Germany: the Ludwigshafen Stroke Study (LuSSt). Stroke, 2010. 41(9): p. 1865-70.
  23. Hallstrom, B., et al., Stroke incidence and survival in the beginning of the 21st century in southern Sweden: comparisons with the late 20th century and projections into the future. Stroke, 2008. 39(1): p. 10-5.
  24. Wawrzynczyk, M., et al., Estimates of stroke incidence and case fatality in Zabrze, 2005-2006. Neurol Neurochir Pol, 2011. 45(1): p. 3-10.
  25. Corso, G., et al., Community-based study of stroke incidence in the Valley of Aosta, Italy. CARe-cerebrovascular Aosta Registry: years 2004-2005. Neuroepidemiology, 2009. 32(3): p. 186-95.
  26. Kolominsky-Rabas, P.L., et al., Time trends in incidence of pathological and etiological stroke subtypes during 16 years: the Erlangen Stroke Project. Neuroepidemiology, 2015. 44(1): p. 24-9.
  27. Kelly, P.J., et al., Incidence, Event Rates, and Early Outcome of Stroke in Dublin, Ireland: The North Dublin Population Stroke Study. Stroke, 2012. 43(8): p. 2042-2047.
  28. Syme, P.D., et al., Community-based stroke incidence in a Scottish population: the Scottish Borders Stroke Study. Stroke, 2005. 36(9): p. 1837-43.
  29. Bejot, Y., et al., Dijon’s vanishing lead with regard to low incidence of stroke, in Eur J Neurol. 2009: England. p. 324-9.
  30. Janes, F., et al., Stroke incidence and 30-day and six-month case fatality rates in Udine, Italy: a population-based prospective study. Int J Stroke, 2013. 8 Suppl A100: p. 100-5.
  31. Timsit, S., et al., High completeness of the brest stroke registry evidenced by analysis of sources and capture-recapture method. Neuroepidemiology, 2014. 42(3): p. 186-95.
  32. Corso, G., et al., Epidemiology of stroke in northern Italy: the Cerebrovascular Aosta Registry, 2004-2008. Neurol Sci, 2013. 34(7): p. 1071-81.
  33. Supanc, V., et al., The evaluation of the stroke unit in Croatia at the University Hospital Sestre milosrdnice, Zagreb: 1995-2006 experience. Coll Antropol, 2009. 33(4): p. 1233-8.
  34. Feigin, V.L., et al., Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol, 2009. 8(4): p. 355-69.
  35. Rothwell, P.M., et al., Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet, 2004. 363(9425): p. 1925-33.
  36. Korv, J. and R. Vibo, Burden of stroke in Estonia. Int J Stroke, 2013. 8(5): p. 372-3.
  37. Vibo, R., J. Kõrv, and M. Roose, The Third Stroke Registry in Tartu, Estonia: Decline of Stroke Incidence and 28-Day Case-Fatality Rate Since 1991. Stroke, 2005. 36(12): p. 2544-2548.
  38. Immonen-Raiha, P., et al., Eleven-year trends of stroke in Turku, Finland. Neuroepidemiology, 2003. 22(3): p. 196-203.
  39. Radisauskas, R., et al., Trends in the Attack Rates, Incidence, and Mortality of Stroke during 1986-2012: Data of Kaunas (Lithuania) Stroke Registry. PLoS One, 2016. 11(4): p. e0153942.
  40. Jorgensen, H.S., et al., Marked increase of stroke incidence in men between 1972 and 1990 in Frederiksberg, Denmark. Stroke, 1992. 23(12): p. 1701-4.
  41. Bejot, Y., et al., Epidemiology of stroke in Europe: geographic and environmental differences. J Neurol Sci, 2007. 262(1-2): p. 85-8.
  42. Sienkiewicz-Jarosz, H., et al., Incidence and case fatality rates of first-ever stroke – comparison of data from two prospective population-based studies conducted in Warsaw, in Neurol Neurochir Pol. 2011: Poland. p. 207-12.
  43. Mihalka, L., et al., A population study of stroke in West Ukraine: incidence, stroke services, and 30-day case fatality. Stroke, 2001. 32(10): p. 2227-31.
  44. Powles, J., et al., Stroke in urban and rural populations in north-east Bulgaria: incidence and case fatality findings from a ‘hot pursuit’ study. BMC Public Health, 2002. 2: p. 24.
  45. Du, X., et al., A community based stroke register in a high risk area for stroke in north west England. J Epidemiol Community Health, 1997. 51(5): p. 472-8.
  46. Lauria, G., et al., Incidence and prognosis of stroke in the Belluno province, Italy. First-year results of a community-based study. Stroke, 1995. 26(10): p. 1787-93.
  47. Vemmos, K.N., et al., Stroke incidence and case fatality in southern Greece: the Arcadia stroke registry. Stroke, 1999. 30(2): p. 363-70.
  48. Di Carlo, A., et al., A prospective community-based study of stroke in Southern Italy: the Vibo Valentia incidence of stroke study (VISS). Methodology, incidence and case fatality at 28 days, 3 and 12 months. Cerebrovasc Dis, 2003. 16(4): p. 410-7.
  49. Ellekjaer, H., et al., Epidemiology of stroke in Innherred, Norway, 1994 to 1996. Incidence and 30-day case-fatality rate. Stroke, 1997. 28(11): p. 2180-4.
  50. Eliasson, J.H., E.M. Valdimarsson, and F. Jakobsson, [Case fatality after acute stroke at the Reykjavik Hospital in 1996-1997.]. Laeknabladid, 1999. 85(6): p. 517-25.
  51. Fekete, K., et al., Prestroke alcohol consumption and smoking are not associated with stroke severity, disability at discharge, and case fatality. J Stroke Cerebrovasc Dis, 2014. 23(1): p. e31-7.
  52. Bereczki, D., et al., The Debrecen Stroke Database: demographic characteristics, risk factors, stroke severity and outcome in 8088 consecutive hospitalised patients with acute cerebrovascular disease. Int J Stroke, 2009. 4(5): p. 335-9.
  53. Appelros, P., et al., Trends in stroke treatment and outcome between 1995 and 2010: observations from Riks-Stroke, the Swedish stroke register. Cerebrovasc Dis, 2014. 37(1): p. 22-9.
  54. Meretoja, A., et al., Stroke monitoring on a national level: PERFECT Stroke, a comprehensive, registry-linkage stroke database in Finland. Stroke, 2010. 41(10): p. 2239-46.
  55. Royal College of Physicians, Sentinel Stroke National Audit Programme (SSNAP) Clinical audit January-March 2016 Public Report: National Results. 2016, Royal College of Physicians: London.
  56. Nichols, M., et al., Cardiovascular disease in Europe 2014: epidemiological update. European Heart Journal, 2014. 35(42): p. 2950-2959.
  57. Kjellstrom, T., B. Norrving, and A. Shatchkute, Helsingborg Declaration 2006 on European stroke strategies. Cerebrovasc Dis, 2007. 23(2-3): p. 231-41.
  58. Kadojic, D., et al., [Prevalence of acute cerebrovascular disease in Bizovac, Osijek-Baranya county: a door-to-door survey in eastern Croatia]. Acta Med Croatica, 2007. 61(3): p. 315-8.
  59. Jungehulsing, G.J., et al., Prevalence of stroke and stroke symptoms: a population-based survey of 28,090 participants. Neuroepidemiology, 2008. 30(1): p. 51-7.
  60. D’Alessandro, G., et al., Prevalence of stroke and stroke-related disability in Valle d’Aosta, Italy. Neurol Sci, 2010. 31(2): p. 137-41.
  61. Orlandi, G., et al., Prevalence of stroke and transient ischaemic attack in the elderly population of an Italian rural community. Eur J Epidemiol, 2003. 18(9): p. 879-82.
  62. Struijs, J.N., et al., Modelling the future burden of stroke in the Netherlands: impact of aging, smoking and hypertension. Stroke, 2005. 36.
  63. Zaletel-Kragelj, L., I. Erzen, and Z. Fras, Interregional differences in health in Slovenia. I. Estimated prevalence of selected cardiovascular and related diseases. Croat Med J, 2004. 45(5): p. 637-43.
  64. Diaz-Guzman, J., et al., Prevalence of stroke and transient ischemic attack in three elderly populations of central Spain. Neuroepidemiology, 2008. 30(4): p. 247-53.
  65. Boix, R., et al., Stroke prevalence among the Spanish elderly: an analysis based on screening surveys. BMC Neurol, 2006. 6: p. 36.
  66. Liebetrau, M., B. Steen, and I. Skoog, Stroke in 85-year-olds: prevalence, incidence, risk factors, and relation to mortality and dementia. Stroke, 2003. 34(11): p. 2617-22.
  67. MacDonald, B.K., et al., The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain, 2000. 123 ( Pt 4): p. 665-76.
  68. Kunst, A.E., M. Amiri, and F. Janssen, The decline in stroke mortality: exploration of future trends in 7 Western European countries. Stroke, 2011. 42(8): p. 2126-30.
  69. Sivenius, J., et al., Continuous 15-year decrease in incidence and mortality of stroke in Finland: the FINSTROKE study. Stroke, 2004. 35(2): p. 420-5.
  70. Bonzini, M., et al., Temporal trends in ischemic and hemorrhagic strokes in Northern Italy: results from the cardiovascular monitoring unit in Northern Italy population-based register, 1998-2004. Neuroepidemiology, 2012. 39(1): p. 35-42.
  71. Tanne, D., et al., Trends in management and outcome of hospitalized patients with acute stroke and transient ischemic attack: the National Acute Stroke Israeli (NASIS) registry. Stroke, 2012. 43(8): p. 2136-41.
  72. Gulliford, M.C., et al., Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management: population-based cohort study. J Neurol Neurosurg Psychiatry, 2010. 81(4): p. 416-22.
  73. Catala-Lopez, F., et al., The national burden of cerebrovascular diseases in Spain: a population-based study using disability-adjusted life years. Med Clin (Barc), 2015. 144(8): p. 353-9.
  74. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet, 2016. 388(10053): p. 1545-1602.
  75. Rudd, A., Personal communication, K.s.C. London, Editor. 2017.
  76. Truelsen, T., et al., Stroke incidence and prevalence in Europe: a review of available data. Eur J Neurol, 2006. 13(6): p. 581-98.
  77. Sivenius, J., et al., Modelling the burden of stroke in Finland until 2030. Int J Stroke, 2009. 4(5): p. 340-5.
  78. Foerch, C., et al., The projected burden of stroke in the German federal state of Hesse up to the year 2050. Dtsch Arztebl Int, 2008. 105(26): p. 467-73.
  79. Smith, S., et al., The future cost of stroke in Ireland: an analysis of the potential impact of demographic change and implementation of evidence-based therapies. Age Ageing, 2013. 42(3): p. 299-306.
  80. La Rosa, F., et al., Stroke care in the next decades: a projection derived from a community-based study in Umbria, Italy. Eur J Epidemiol, 1993. 9(2): p. 151-4.
  81. Malmgren, R., et al., Projecting the number of patients with first ever strokes and patients newly handicapped by stroke in England and Wales. Bmj, 1989. 298(6674): p. 656-60.
  82. European Heart Network, European Cardiovascular Disease Statistics. 2017.
  83. Organisation for Economic Cooperation and Development, Health at a Glance: Europe 2016. OECD Publishing.
  84. Di Carlo, A., Human and economic burden of stroke. Age Ageing, 2009. 38(1): p. 4-5.
  85. O’Donnell, M.J., et al., Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. Lancet, 2016. 388(10046): p. 761-75.
  86. World Health Organisation, Global Health Observatory data repository. WHO: http://apps.who.int/gho.
  87. Dokova, K.G., et al., Public understanding of the causes of high stroke risk in northeast Bulgaria. Eur J Public Health, 2005. 15(3): p. 313-6.
  88. Kanisek, S.P., N.; Barac, I., Perceptions of stroke among patients with an increased risk of stroke. South Eastern Europe Health Sciences Journal (SEEHSJ), 2012. 2(2): p. 75-81.
  89. Truelsen, T. and L.H. Krarup, Stroke awareness in Denmark. Neuroepidemiology, 2010. 35(3): p. 165-70.
  90. Vibo, R., et al., Stroke awareness in two Estonian cities: better knowledge in subjects with advanced age and higher education. Eur Neurol, 2013. 69(2): p. 89-94.
  91. Worthmann, H., et al., Educational campaign on stroke in an urban population in Northern Germany: influence on public stroke awareness and knowledge. International Journal of Stroke, 2013. 8(5): p. 286-292.
  92. Ntaios, G., et al., Poor Stroke Risk Perception despite Moderate Public Stroke Awareness: Insight from a Cross-sectional National Survey in Greece. Journal of Stroke and Cerebrovascular Diseases, 2015. 24(4): p. 721-724.
  93. Hickey, A., et al., Knowledge of stroke risk factors and warning signs in Ireland: development and application of the Stroke Awareness Questionnaire (SAQ). Int J Stroke, 2012. 7(4): p. 298-306.
  94. Nordanstig, A., K. Jood, and L. Rosengren, Public stroke awareness and intent to call 112 in Sweden. Acta Neurologica Scandinavica, 2014. 130(6): p. 400-404.
  95. Proietti, M., et al., A population screening programme for atrial fibrillation: a report from the Belgian Heart Rhythm Week screening programme. Europace, 2016.
  96. Mikulik, R., et al., Calling 911 in response to stroke: no change following a four-year educational campaign. Cerebrovasc Dis, 2011. 32(4): p. 342-8.
  97. Marx, J.J., et al., An educational multimedia campaign has differential effects on public stroke knowledge and care-seeking behavior. Journal of Neurology, 2008. 255.
  98. Brainin, M., et al., Acute neurological stroke care in Europe: results of the European Stroke Care Inventory. Eur J Neurol, 2000. 7(1): p. 5-10.
  99. De Macedo, M.E., et al., Prevalence, awareness, treatment and control of hypertension in Portugal. The PAP study. Rev Port Cardiol, 2007. 26(1): p. 21-39.
  100. Banegas, J.R., et al., Trends in hypertension control among the older population of Spain from 2000 to 2001 to 2008 to 2010: role of frequency and intensity of drug treatment. Circ Cardiovasc Qual Outcomes, 2015. 8(1): p. 67-76.
  101. Tocci, G., et al., Blood pressure levels and control in Italy: comprehensive analysis of clinical data from 2000-2005 and 2005-2011 hypertension surveys. J Hum Hypertens, 2015. 29(11): p. 696-701.
  102. Neuhauser, H.K., et al., Hypertension prevalence, awareness, treatment and control in Germany 1998 and 2008-11. J Hum Hypertens, 2015. 29(4): p. 247-53.
  103. Diederichs, C. and H. Neuhauser, Regional variations in hypertension prevalence and management in Germany: results from the German Health Interview and Examination Survey (DEGS1). J Hypertens, 2014. 32(7): p. 1405-13; discussion 1414.
  104. Bembenek, J.P., et al., Temporal trends in vascular risk factors and etiology of urban Polish stroke patients from 1995 to 2013. J Neurol Sci, 2015. 357(1-2): p. 126-30.
  105. Marshall, I.J., et al., Trends in risk factor prevalence and management before first stroke: data from the South London Stroke Register 1995-2011. Stroke, 2013. 44(7): p. 1809-16.
  106. Lee, S., A.C. Shafe, and M.R. Cowie, UK stroke incidence, mortality and cardiovascular risk management 1999-2008: time-trend analysis from the General Practice Research Database. BMJ Open, 2011. 1(2): p. e000269.
  107. De Backer, G., et al., Lifestyle and risk factor management in people at high cardiovascular risk from Bulgaria, Croatia, Poland, Romania and the United Kingdom who participated in both the EUROASPIRE III and IV primary care surveys. Eur J Prev Cardiol, 2016. 23(15): p. 1618-27.
  108. Banegas, J.R., et al., Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: the EURIKA study. Eur Heart J, 2011. 32(17): p. 2143-52.
  109. Rohla, M., et al., Awareness, treatment, and control of hypertension in Austria: a multicentre cross-sectional study. J Hypertens, 2016. 34(7): p. 1432-40.
  110. De Giusti, M., et al., A survey on blood pressure levels and hypertension control in a sample of the Italian general population. High Blood Press Cardiovasc Prev, 2012. 19(3): p. 129-35.
  111. Efstratopoulos, A.D., et al., Prevalence, awareness, treatment and control of hypertension in Hellas, Greece: the Hypertension Study in General Practice in Hellas (HYPERTENSHELL) national study. Am J Hypertens, 2006. 19(1): p. 53-60.
  112. Neuhauser, H., et al., Hypertension in Germany. Dtsch Arztebl Int, 2016. 113(48): p. 809-815.
  113. Morgado, M.P., et al., Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal. BMC Health Serv Res, 2010. 10: p. 349.
  114. Jensdottir, J.O., E.L. Sigurethsson, and G. Thornorgeirsson, [Hypertension management in general practice in Iceland]. Laeknabladid, 2006. 92(5): p. 375-80.
  115. Heuschmann, P.U., et al., Control of main risk factors after ischaemic stroke across Europe: data from the stroke-specific module of the EUROASPIRE III survey. Eur J Prev Cardiol, 2015. 22(10): p. 1354-62.
  116. Brewer, L., et al., Secondary prevention after ischaemic stroke: the ASPIRE-S study. BMC Neurol, 2015. 15: p. 216.
  117. Krijthe, B.P., et al., Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J, 2013. 34(35): p. 2746-51.
  118. Ball, J., et al., Atrial fibrillation: profile and burden of an evolving epidemic in the 21st century. Int J Cardiol, 2013. 167(5): p. 1807-24.
  119. Hobbs, F.D., Stroke detection and prevention in atrial fibrillation. Br J Gen Pract, 2015. 65(636): p. 332-3.
  120. Jorgensen, H.S., et al., Acute stroke with atrial fibrillation. The Copenhagen Stroke Study. Stroke, 1996. 27(10): p. 1765-9.
  121. Healey, J.S., et al., Occurrence of death and stroke in patients in 47 countries 1 year after presenting with atrial fibrillation: a cohort study. Lancet, 2016. 388(10050): p. 1161-9.
  122. Kirchhof, P., et al., 2016 ESC Guidelines for the Management of Atrial Fibrillation Developed in Collaboration With EACTS. Rev Esp Cardiol (Engl Ed), 2017. 70(1): p. 50.
  123. Bonhorst, D., et al., Prevalence of atrial fibrillation in the Portuguese population aged 40 and over: the FAMA study. Rev Port Cardiol, 2010. 29(3): p. 331-50.
  124. Kearney, M., M. Fay, and D.A. Fitzmaurice, Stroke prevention in atrial fibrillation: we can do better. British Journal of General Practice, 2016. 66(643): p. 62-63.
  125. Gomez-Doblas, J.J., et al., Prevalence of atrial fibrillation in Spain. OFRECE study results, in Rev Esp Cardiol (Engl Ed). 2014, 2013 Sociedad Espanola de Cardiologia. Published by Elsevier Espana: Spain. p. 259-69.
  126. Fitzmaurice, D.A., et al., Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trial. Bmj, 2007. 335(7616): p. 383.
  127. Svennberg, E., et al., Mass Screening for Untreated Atrial Fibrillation: The STROKESTOP Study. Circulation, 2015. 131(25): p. 2176-84.
  128. Sacco, S., et al., Epidemiology of stroke in Italy. Int J Stroke, 2011. 6(3): p. 219-27.
  129. McElwaine, P., J. McCormack, and J. Harbison, Irish Heart Foundation/HSE National Stroke Audit 2015. 2015.
  130. Pikija, S., et al., A High Burden of Ischemic Stroke in Regions of Eastern/Central Europe is Largely Due to Modifiable Risk Factors. Curr Neurovasc Res, 2015. 12(4): p. 341-52.
  131. Naess, H., et al., [Patients with acute cerebral infarction admitted to stroke unit]. Tidsskr Nor Laegeforen, 2011. 131(8): p. 814-8.
  132. Sposato, L.A., et al., Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol, 2015. 14(4): p. 377-87.
  133. Heeringa, J., et al., Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study, in Eur Heart J. 2006: England. p. 949-53.
  134. Stefansdottir, H., et al., Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections, in Europace. 2011: England. p. 1110-7.
  135. Yiin, G.S., et al., Age-specific incidence, outcome, cost, and projected future burden of atrial fibrillation-related embolic vascular events: a population-based study. Circulation, 2014. 130(15): p. 1236-44.
  136. Hobbs, F.R., et al., European Primary Care Cardiovascular Society (EPCCS) consensus guidance on stroke prevention in atrial fibrillation (SPAF) in primary care. European journal of preventive cardiology, 2016. 23(5): p. 460-473.
  137. Camm, A.J., et al., 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation–developed with the special contribution of the European Heart Rhythm Association. Europace, 2012. 14(10): p. 1385-413.
  138. Kirchhof, P., et al., Management of atrial fibrillation in seven European countries after the publication of the 2010 ESC Guidelines on atrial fibrillation: primary results of the PREvention oF thromboemolic events—European Registry in Atrial Fibrillation (PREFER in AF). Europace, 2014. 16(1): p. 6-14.
  139. Lip, G.Y., et al., Regional differences in presentation and treatment of patients with atrial fibrillation in Europe: a report from the EURObservational Research Programme Atrial Fibrillation (EORP-AF) Pilot General Registry. Europace, 2015. 17(2): p. 194-206.
  140. Proietti, M., et al., Real-world’ atrial fibrillation management in Europe: observations from the 2-year follow-up of the EURObservational Research Programme-Atrial Fibrillation General Registry Pilot Phase. Europace, 2016.
  141. Potpara, T.S., et al., Stroke prevention in atrial fibrillation and ‘real world’ adherence to guidelines in the Balkan Region: The BALKAN-AF Survey. Sci Rep, 2016. 6: p. 20432.
  142. Nieuwlaat, R., et al., Atrial fibrillation management: a prospective survey in ESC member countries: the Euro Heart Survey on Atrial Fibrillation. Eur Heart J, 2005. 26(22): p. 2422-34.
  143. Kakkar, A.K., et al., Risk profiles and antithrombotic treatment of patients newly diagnosed with atrial fibrillation at risk of stroke: perspectives from the international, observational, prospective GARFIELD registry. PLoS One, 2013. 8(5): p. e63479.
  144. Oldgren, J., et al., Variations in cause and management of atrial fibrillation in a prospective registry of 15,400 emergency department patients in 46 countries: the RE-LY Atrial Fibrillation Registry. Circulation, 2014. 129(15): p. 1568-76.
  145. Huisman, M.V., et al., Antithrombotic therapy use in patients with atrial fibrillation before the era of non-vitamin K antagonist oral anticoagulants: the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) Phase I cohort. Europace, 2016. 18(9): p. 1308-18.
  146. Lip, G.Y., et al., ‘Real-world’ antithrombotic treatment in atrial fibrillation: The EORP-AF pilot survey. Am J Med, 2014. 127(6): p. 519-29.e1.
  147. Brandes, A., et al., Guideline adherence of antithrombotic treatment initiated by general practitioners in patients with nonvalvular atrial fibrillation: a Danish survey. Clin Cardiol, 2013. 36(7): p. 427-32.
  148. Gadsboll, K., et al., Increased use of oral anticoagulants in patients with atrial fibrillation: temporal trends from 2005 to 2015 in Denmark. Eur Heart J, 2017.
  149. Nabauer, M., et al., The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management. Europace, 2009. 11(4): p. 423-34.
  150. Ninios, I., et al., Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural Greece. J Thromb Thrombolysis, 2010. 30(1): p. 90-6.
  151. Korantzopoulos, P., et al., Atrial fibrillation and thromboembolic risk in Greece. Hellenic J Cardiol, 2012. 53(1): p. 48-54.
  152. Piccinocchi, G., et al., Diagnosis and management of atrial fibrillation by primary care physicians in Italy : a retrospective, observational analysis. Clin Drug Investig, 2012. 32(11): p. 771-7.
  153. Bednarski, J., et al., Anticoagulant and antiplatelet therapy for stroke prevention in atrial fibrillation patients in the clinical practice of a single district hospital in Poland. Kardiol Pol, 2013. 71(12): p. 1260-5.
  154. Clua-Espuny, J.L., et al., Prevalence of undiagnosed atrial fibrillation and of that not being treated with anticoagulant drugs: the AFABE study. Rev Esp Cardiol (Engl Ed), 2013. 66(7): p. 545-52.
  155. Friberg, L. and L. Bergfeldt, Atrial fibrillation prevalence revisited. J Intern Med, 2013. 274(5): p. 461-8.
  156. DeWilde, S., et al., Trends in the prevalence of diagnosed atrial fibrillation, its treatment with anticoagulation and predictors of such treatment in UK primary care. Heart, 2006. 92(8): p. 1064-70.
  157. Asberg, S., et al., Ischemic stroke and secondary prevention in clinical practice: a cohort study of 14,529 patients in the Swedish Stroke Register. Stroke, 2010. 41(7): p. 1338-42.
  158. Steger, C., et al., Stroke patients with atrial fibrillation have a worse prognosis than patients without: data from the Austrian Stroke registry. Eur Heart J, 2004. 25(19): p. 1734-40.
  159. Palomaki, A., et al., Underuse of anticoagulation in stroke patients with atrial fibrillation–the FibStroke Study. Eur J Neurol, 2016. 23(1): p. 133-9.
  160. Friberg, L., et al., High prevalence of atrial fibrillation among patients with ischemic stroke. Stroke, 2014. 45(9): p. 2599-605.
  161. Royal College of Physicians, Sentinel Stroke National Audit Programme (SSNAP) Post-acute organisational audit: Public Report Phase 2. 2015, Royal College of Physicians: London.
  162. Ayis, S.A., et al., Variations in acute stroke care and the impact of organised care on survival from a European perspective: the European Registers of Stroke (EROS) investigators. J Neurol Neurosurg Psychiatry, 2013. 84(6): p. 604-12.
  163. Hillmann, S., et al., Temporal Changes in the Quality of Acute Stroke Care in Five National Audits across Europe. Biomed Res Int, 2015. 2015: p. 432497.
  164. Pardo Cabello, A.J., et al., Implementation of clinical practice guidelines for acute ischaemic stroke in specialist care centres. Neurologia, 2013. 28(3): p. 137-44.
  165. NHS England, Medicines Optimization Dashboard, November 2015 Version. https://www.england.nhs.uk.ourwork/pe/mo-dash/.
  166. Gorczyca-Michta, I. and B. Wozakowska-Kaplon, New oral anticoagulants for the prevention of thromboembolic complications in atrial fibrillation: a single centre experience. Kardiol Pol, 2015. 73(2): p. 85-93.
  167. Luger, S., et al., Prescription frequency and predictors for the use of novel direct oral anticoagulants for secondary stroke prevention in the first year after their marketing in Europe–a multicentric evaluation. Int J Stroke, 2014. 9(5): p. 569-75.
  168. Le Heuzey, J.Y., et al., Differences among western European countries in anticoagulation management of atrial fibrillation. Data from the PREFER IN AF registry. Thromb Haemost, 2014. 111(5): p. 833-41.
  169. Amarenco, P., et al., One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke. N Engl J Med, 2016. 374(16): p. 1533-42.
  170. Cancelli, I., et al., Incidence of transient ischemic attack and early stroke risk: validation of the ABCD2 score in an Italian population-based study. Stroke, 2011. 42(10): p. 2751-7.
  171. Lovett, J.K., et al., Very early risk of stroke after a first transient ischemic attack. Stroke, 2003. 34(8): p. e138-40.
  172. Johnston, S.C., et al., Short-term prognosis after emergency department diagnosis of TIA. Jama, 2000. 284(22): p. 2901-6.
  173. Dutta, D., E. Bowen, and C. Foy, Four-year follow-up of transient ischemic attacks, strokes, and mimics: a retrospective transient ischemic attack clinic cohort study. Stroke, 2015. 46(5): p. 1227-32.
  174. Valls, J., et al., A Current Estimation of the Early Risk of Stroke after Transient Ischemic Attack: A Systematic Review and Meta-Analysis of Recent Intervention Studies. Cerebrovasc Dis, 2017. 43(1-2): p. 90-98.
  175. Kokubo, Y., Epidemiology of transient ischemic attack. Front Neurol Neurosci, 2014. 33: p. 69-81.
  176. Tavosian, A., J.O. Strom, and P. Appelros, Incidence of Transient Ischemic Attacks in Sweden. Neuroepidemiology, 2016. 47(1): p. 20-5.
  177. Kadojic, D., et al., Incidence of Stroke and Transient Ischemic Attack in Croatia: A Population Based Study. Coll Antropol, 2015. 39(3): p. 723-7.
  178. King’s College London, Stroke researcher/patient organisation response to Stroke Association questions. 2016.
  179. Lavallee, P.C., et al., A transient ischaemic attack clinic with round-the-clock access (SOS-TIA): feasibility and effects. Lancet Neurol, 2007. 6(11): p. 953-60.
  180. Evenson, K.R., et al., A comprehensive review of prehospital and in-hospital delay times in acute stroke care. Int J Stroke, 2009. 4(3): p. 187-99.
  181. Jungehulsing, G.J., et al., Emergency department delays in acute stroke – analysis of time between ED arrival and imaging. Eur J Neurol, 2006. 13(3): p. 225-32.
  182. Koutlas, E., et al., Factors influencing the pre- and in-hospital management of acute stroke–data from a Greek tertiary care hospital. Eur Neurol, 2004. 51(1): p. 35-7.
  183. Maestroni, A., et al., Factors influencing delay in presentation for acute stroke in an emergency department in Milan, Italy. Emerg Med J, 2008. 25(6): p. 340-5.
  184. Lindsberg, P.J., et al., Door to thrombolysis: ER reorganization and reduced delays to acute stroke treatment. Neurology, 2006. 67(2): p. 334-6.
  185. Haass, A., et al., [“Time is brain”. Optimizing prehospital stroke management]. Nervenarzt, 2014. 85(2): p. 189-94.
  186. Ragoschke-Schumm, A., et al., Translation of the ‘time is brain’ concept into clinical practice: focus on prehospital stroke management. Int J Stroke, 2014. 9(3): p. 333-40.
  187. Boode, B., et al., Estimating the number of stroke patients eligible for thrombolytic treatment if delay could be avoided. Cerebrovasc Dis, 2007. 23(4): p. 294-8.
  188. Mata, J., R. Frank, and G. Gigerenzer, Symptom recognition of heart attack and stroke in nine European countries: a representative survey. Health Expectations, 2014. 17(3): p. 376-387.
  189. E. Titianova, I.V., B. Stamenov, Treatment of Acute Ischemic Stroke with Thrombolysis in Bulgaria. 2010: Bulgarian Society of Neurosonology and Cerebral Hemodynamics.
  190. Mikulik, R., et al., Calling 911 in response to stroke: a nationwide study assessing definitive individual behavior. Stroke, 2008. 39(6): p. 1844-9.
  191. Gache, K., et al., Main barriers to effective implementation of stroke care pathways in France: a qualitative study. BMC Health Services Research, 2014. 14: p. 95-95.
  192. Hickey, A., et al., Stroke awareness in the general population: knowledge of stroke risk factors and warning signs in older adults. BMC geriatrics, 2009. 9(1): p. 1.
  193. Mazzucco, S., et al., What is still missing in acute-phase treatment of stroke: a prospective observational study. Neurol Sci, 2013. 34(4): p. 449-55.
  194. Vilionskis, A.J., D.; Duobaite, Z.M., The accessibility of intravenous thrombolysis for acute ischemic stroke patients in Lithuania. 2009: Poster presentation at Baltic Conference 2009.
  195. Ana Sofia Duque, L.F., Ana Filipa Correia, Inês Calvinho, Gonçalo Cardoso, Marta Pinto, Patricia Freitas, Joana Silvestre, Vitor Batalha, Luis Campos, AWARENESS OF STROKE RISK FACTORS AND WARNING SIGNS AND ATTITUDE TO ACUTE STROKE. international archives of medicine, 2015. 8.
  196. Lundelin, K., et al., Knowledge of stroke warning symptoms and intended action in response to stroke in Spain: a nationwide population-based study. Cerebrovasc Dis, 2012. 34(2): p. 161-8.
  197. Nordanstig, A., K. Jood, and L. Rosengren, Public stroke awareness and intent to call 112 in Sweden. Acta Neurol Scand, 2014. 130(6): p. 400-4.
  198. Lecouturier, J., et al., Response to symptoms of stroke in the UK: a systematic review, in BMC Health Services Research. 2010.
  199. Silvestrelli, G., et al., Characteristics of delayed admission to stroke unit. Clin Exp Hypertens, 2006. 28(3-4): p. 405-11.
  200. Wolters, F.J., et al., Sustained impact of UK FAST-test public education on response to stroke: a population-based time-series study. Int J Stroke, 2015. 10(7): p. 1108-14.
  201. Flynn, D., et al., A Time Series Evaluation of the FAST National Stroke Awareness Campaign in England. PLoS One, 2014. 9(8).
  202. Mellon, L., et al., Can a media campaign change health service use in a population with stroke symptoms? Examination of the first Irish stroke awareness campaign. Emerg Med J, 2013.
  203. Muller-Nordhorn, J., et al., Population-based intervention to reduce prehospital delays in patients with cerebrovascular events, in Arch Intern Med. 2009: United States. p. 1484-90.
  204. Marx, J.J., et al., Gender-specific differences in stroke knowledge, stroke risk perception and the effects of an educational multimedia campaign. J Neurol, 2010. 257(3): p. 367-74.
  205. Lecouturier, J., et al., Systematic review of mass media interventions designed to improve public recognition of stroke symptoms, emergency response and early treatment. BMC Public Health, 2010. 10: p. 784.
  206. Rasura, M., et al., Effectiveness of public stroke educational interventions: a review. Eur J Neurol, 2014. 21(1): p. 11-20.
  207. Behrens, S., et al., Improvement in stroke quality management by an educational programme. Cerebrovasc Dis, 2002. 13(4): p. 262-6.
  208. Puolakka, T., et al., Cutting the Prehospital On-Scene Time of Stroke Thrombolysis in Helsinki: A Prospective Interventional Study. Stroke, 2016. 47(12): p. 3038-3040.
  209. Willeit, J., et al., Thrombolysis and clinical outcome in patients with stroke after implementation of the Tyrol Stroke Pathway: a retrospective observational study. Lancet Neurol, 2015. 14(1): p. 48-56.
  210. Meretoja, A., et al., Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology, 2012. 79(4): p. 306-13.
  211. Heikkila, I., et al., Stroke thrombolysis given by emergency physicians cuts in-hospital delays significantly immediately after implementing a new treatment protocol. Scand J Trauma Resusc Emerg Med, 2016. 24: p. 46.
  212. Dequatre-Ponchelle, N., et al., Rate of intravenous thrombolysis for acute ischaemic stroke in the North-of-France region and evolution over time, in Journal of Neurology. 2014. p. 1320-1328.
  213. Egi, C., et al., Improving Outcomes Achieved by a New Stroke Program in Hungary. Cerebrovasc Dis Extra, 2015. 5(3): p. 132-8.
  214. Baldereschi, M., et al., Relevance of prehospital stroke code activation for acute treatment measures in stroke care: a review. Cerebrovasc Dis, 2012. 34(3): p. 182-90.
  215. Silva, S. and M. Gouveia, Program “Via verde do AVC”: analysis of the impact on stroke mortality. Revista Portuguesa de Saúde Pública, 2012. 30(2): p. 172-179.
  216. Moutinho, M., et al., [A community-based study of stroke code users in northern Portugal]. Acta Med Port, 2013. 26(2): p. 113-22.
  217. Abilleira, S., et al., Outcomes of Intravenous Thrombolysis After Dissemination of the Stroke Code and Designation of New Referral Hospitals in Catalonia. Stroke, 2011. 42(7): p. 2001-2006.
  218. Belvis, R., et al., Benefits of a prehospital stroke code system. Feasibility and efficacy in the first year of clinical practice in Barcelona, Spain. Cerebrovasc Dis, 2005. 19(2): p. 96-101.
  219. de la Ossa, N.P., et al., Influence of the stroke code activation source on the outcome of acute ischemic stroke patients. Neurology, 2008. 70(15): p. 1238-43.
  220. Clinical Standards Committee, B.A.o.S.P., Stroke Services Standards. 2014: UK.
  221. Meretoja, A., et al., Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months. Neurology, 2013. 81(12): p. 1071-6.
  222. Mikulik, R., et al., Factors influencing in-hospital delay in treatment with intravenous thrombolysis. Stroke, 2012. 43(6): p. 1578-83.
  223. Harsany, M., et al., Factors influencing door-to-imaging time: analysis of the safe implementation of treatments in Stroke-EAST registry. J Stroke Cerebrovasc Dis, 2014. 23(8): p. 2122-9.
  224. Scherf, S., et al., Increase in national intravenous thrombolysis rates for ischaemic stroke between 2005 and 2012: is bigger better? BMC Neurol, 2016. 16: p. 53.
  225. Strbian, D., et al., Trends in Door-to-Thrombolysis Time in the Safe Implementation of Stroke Thrombolysis Registry: Effect of Center Volume and Duration of Registry Membership. Stroke, 2015. 46(5): p. 1275-80.
  226. Stroke Unit Trialists’ Collaboration, Organised inpatient (stroke unit) care for stroke. Cochrane Database Syst Rev, 2013(9): p. Cd000197.
  227. Norrving, B., The 2006 Helsingborg Consensus Conference on European Stroke Strategies: Summary of conference proceedings and background to the 2nd Helsingborg Declaration. Int J Stroke, 2007. 2(2): p. 139-43.
  228. Mikulik, R., V. Caso, and N. Wahlgren, Past and Future of Stroke Care in Europe. 2017: ORUEN – The CNS Journal. p. 19-26.
  229. Czlonkowska, A., M. Skowroñska, and M. Niewada, Stroke Service in Central and Eastern Europe. International Journal of Stroke, 2007. 2(4): p. 276-278.
  230. Budincevic, H., et al., Management of ischemic stroke in Central and Eastern Europe. Int J Stroke, 2015. 10 Suppl A100: p. 125-7.
  231. Diez-Tejedor, E. and B. Fuentes, Stroke care in Spain. What do we have? What do we need? Neurologia, 2011. 26(8): p. 445-8.
  232. Lopez Fernandez, J.C., et al., Analysis of stroke care resources in Spain in 2012: have we benefitted from the Spanish Health System’s stroke care strategy? Neurologia, 2014. 29(7): p. 387-96.
  233. Abilleira, S., et al., The Second Stroke Audit of Catalonia shows improvements in many, but not all quality indicators. Int J Stroke, 2012. 7(1): p. 19-24.
  234. Meretoja, A., et al., Trends in treatment and outcome of stroke patients in Finland from 1999 to 2007. PERFECT Stroke, a nationwide register study. Ann Med, 2011. 43 Suppl 1: p. S22-30.
  235. Czlonkowska, A., et al., Ten years of stroke programmes in Poland: where did we start? Where did we get to? Int J Stroke, 2010. 5(5): p. 414-6.
  236. Sarzynska-Dlugosz, I., M. Skowronska, and A. Czlonkowska, Organization of acute stroke services in Poland – Polish Stroke Unit Network development. Neurol Neurochir Pol, 2013. 47(1): p. 3-7.
  237. Royal College of Physicians, Mind the Gap! The Third SSNAP Annual Report. Care received between April 2015 to March 2016. 2016, Royal College of Physicians: London.
  238. Wiedmann, S., et al., The quality of acute stroke care-an analysis of evidence-based indicators in 260 000 patients. Dtsch Arztebl Int, 2014. 111(45): p. 759-765.
  239. Serles, W., et al., Endovascular stroke therapy in Austria: a nationwide 1-year experience. Eur J Neurol, 2016. 23(5): p. 906-11.
  240. Sunol, R., et al., Implementation of Departmental Quality Strategies Is Positively Associated with Clinical Practice: Results of a Multicenter Study in 73 Hospitals in 7 European Countries. PLoS One, 2015. 10(11): p. e0141157.
  241. Schmidt, A., et al., Acute Ischemic Stroke (AIS) patient management in French stroke units and impact estimation of thrombolysis on care pathways and associated costs, in Cerebrovasc Dis. 2015, 2015 S. Karger AG, Basel.: Switzerland. p. 94-101.
  242. Ferro, S., et al., Stroke care policy and management in Italy. Progress in Neuroscience, 2013. 1.
  243. Micallef, D., et al., Auditing thrombolysis service for stroke at Mater Dei Hospital. Malta Medical Journal, 2015. 27(01).
  244. Di Carlo, A., et al., Methods of Implementation of Evidence-Based Stroke Care in Europe: European Implementation Score Collaboration. Stroke, 2015. 46(8): p. 2252-9.
  245. Hofer, C., S. Kiechl, and W. Lang, [The Austrian Stroke-Unit-Registry]. Wien Med Wochenschr, 2008. 158(15-16): p. 411-7.
  246. Malmivaara, A., et al., Comparing ischaemic stroke in six European countries. The EuroHOPE register study. European Journal of Neurology, 2015. 22(2): p. 284-e26.
  247. Leys, D., et al., The main components of stroke unit care: results of a European expert survey. Cerebrovasc Dis, 2007. 23(5-6): p. 344-52.
  248. Leys, D., et al., Facilities Available in European Hospitals Treating Stroke Patients. Stroke, 2007. 38(11): p. 2985-2991.
  249. Tomek, A., Stroke Care in the Czech Republic, in Cerebrovascular Section of Czech Neurologic Society. 2014.
  250. Douw, K., C.P. Nielsen, and C.R. Pedersen, Centralising acute stroke care and moving care to the community in a Danish health region: Challenges in implementing a stroke care reform. Health Policy, 2015. 119(8): p. 1005-1010.
  251. Ramsay, A.I., et al., Effects of Centralizing Acute Stroke Services on Stroke Care Provision in Two Large Metropolitan Areas in England. Stroke, 2015. 46(8): p. 2244-51.
  252. Morris, S., et al., Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis. Bmj, 2014. 349: p. g4757.
  253. Physicians, R.C.o., Sentinel Stroke National Audit Programme, Acute organisational audit report. 2014.
  254. Ringelstein, E.B., et al., European Stroke Organisation recommendations to establish a stroke unit and stroke center. Stroke, 2013. 44(3): p. 828-40.
  255. Wardlaw JM, M.V., Berge E, del Zoppo GJ, Thrombolysis for acute ischaemic stroke. Cochrane Database of Systematic Reviews, 2009.
  256. Brozman, M.N.U.H., Management of stroke patients and stroke registry in Slovak Republic. 2009.
  257. Lenti, L., et al., Stroke care in Central Eastern Europe: current problems and call for action. Int J Stroke, 2013. 8(5): p. 365-71.
  258. Lenti, L., et al., Stroke care in Central Eastern Europe: current problems and call for action. International Journal of Stroke, 2013. 8(5): p. 365-371.
  259. Droste, D.W. and R. Metz, [Actual state and prospects of acute stroke treatment in the Grand-Duchy of Luxemburg]. Bull Soc Sci Med Grand Duche Luxemb, 2011(2): p. 25-33.
  260. Tanne, D., Endovascular Treatment for Acute Large Artery Occlusion Stroke: Implications for Israel. Israel Medicine Association Journal,, 2016. 18: p. 2-3.
  261. Sorensen, T., et al., A qualitative description of telemedicine for acute stroke care in Norway: technology is not the issue. BMC Health Serv Res, 2014. 14: p. 643.
  262. Scotland, N.N.H.S., Scottish Stroke Care Audit: 2014 National Report of Stroke Services in Scottish Hospitals. http://www.strokeaudit.scot.nhs.uk.
  263. Scholten, N., et al., [Thrombolysis for acute stroke–a nationwide analysis of regional medical care]. Fortschr Neurol Psychiatr, 2013. 81(10): p. 579-85.
  264. Stolz, E., et al., Regional differences in acute stroke admission and thrombolysis rates in the German federal state of Hesse. Dtsch Arztebl Int, 2011. 108(36): p. 607-11.
  265. Bauer, A., M. Limburg, and M.C. Visser, Variation in clinical practice of intravenous thrombolysis in stroke in the Netherlands. Cerebrovasc Dis Extra, 2013. 3(1): p. 74-7.
  266. Eriksson, M., et al., Dissemination of thrombolysis for acute ischemic stroke across a nation: experiences from the Swedish stroke register, 2003 to 2008. Stroke, 2010. 41(6): p. 1115-22.
  267. Popova, K., Evidence-based guidelines in Bulgaria: A new frontier for management of stroke in primary care. 2012.
  268. Szel, I., et al., Acute care and rehabilitation of patients with stroke in Hungary. Am J Phys Med Rehabil, 2009. 88(7): p. 601-4.
  269. Kozera, G., et al., Pre-hospital delays and intravenous thrombolysis in urban and rural areas. Acta Neurol Scand, 2012. 126(3): p. 171-7.
  270. Mikulik, R., et al., A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic. J Neurol, 2010. 257(1): p. 31-7.
  271. van Dishoeck, A.M., et al., Measuring Quality Improvement in Acute Ischemic Stroke Care: Interrupted Time Series Analysis of Door-to-Needle Time. Cerebrovasc Dis Extra, 2014. 4(2): p. 149-55.
  272. Gumbrevicius, G.R., D.; Lauckaite, K.; Krasauskaite, E.; Urbonaviciute, I.; Sveikata, A.; Janusonis T., Acute ischemic stroke care in two hospitals of Lithuania: Issues on its compliance with international and national guidelines. A retrospective study. Sveikatos Mokslai, 2011. 21(4): p. 100-108.
  273. Norrving, B., et al., Cross-national key performance measures of the quality of acute stroke care in Western Europe. Stroke, 2015. 46(10): p. 2891-2895.
  274. Paul, C.L., et al., How can we improve stroke thrombolysis rates? A review of health system factors and approaches associated with thrombolysis administration rates in acute stroke care. Implement Sci, 2016. 11: p. 51.
  275. Etgen, T., et al., Multimodal strategy in the successful implementation of a stroke unit in a community hospital. Acta Neurol Scand, 2011. 123(6): p. 390-5.
  276. Minnerup, J., et al., Impact of the extended thrombolysis time window on the proportion of recombinant tissue-type plasminogen activator-treated stroke patients and on door-to-needle time. Stroke, 2011. 42(10): p. 2838-43.
  277. Arkuszewski, M., et al., Intravenous thrombolysis in acute ischemic stroke after POLKARD: one center analysis of program impact on clinical practice. Adv Med Sci, 2011. 56(2): p. 231-40.
  278. Toni, D., et al., Intravenous thrombolysis and intra-arterial interventions in acute ischemic stroke: Italian Stroke Organisation (ISO)-SPREAD guidelines. Int J Stroke, 2015. 10(7): p. 1119-29.
  279. Kwan, J., P. Hand, and P. Sandercock, A systematic review of barriers to delivery of thrombolysis for acute stroke. Age Ageing, 2004. 33(2): p. 116-21.
  280. Slot, K.B., et al., Thrombolytic treatment for stroke in the Scandinavian countries. Acta Neurol Scand, 2009. 120(4): p. 270-6.
  281. Faiz, K.W., et al., Reasons for low thrombolysis rate in a Norwegian ischemic stroke population. Neurol Sci, 2014. 35(12): p. 1977-82.
  282. Tveiten, A., et al., Intravenous thrombolysis for ischaemic stroke: short delays and high community-based treatment rates after organisational changes in a previously inexperienced centre. Emerg Med J, 2009. 26(5): p. 324-6.
  283. Rudd, A.G., et al., Stroke thrombolysis in England, Wales and Northern Ireland: how much do we do and how much do we need? J Neurol Neurosurg Psychiatry, 2011. 82(1): p. 14-9.
  284. Lahr, M.M., et al., Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting. Stroke, 2012. 43(5): p. 1336-40.
  285. van den Berg, J.S. and G. de Jong, Why ischemic stroke patients do not receive thrombolytic treatment: results from a general hospital. Acta Neurol Scand, 2009. 120(3): p. 157-60.
  286. Kohrmann, M., et al., Avoiding in hospital delays and eliminating the three-hour effect in thrombolysis for stroke. Int J Stroke, 2011. 6(6): p. 493-7.
  287. Bodiguel, E., et al., [Influence of acute stroke care organization on the implementation of clinical practice guidelines], in Rev Neurol (Paris). 2009: France. p. 949-56.
  288. Santana, S.N., C.; Rente, J., Current status and developments in the care of stroke patients in Portugal. 2011: Igitur publishing.
  289. Bray, B.D., et al., Bigger, faster? Associations between hospital thrombolysis volume and speed of thrombolysis administration in acute ischemic stroke. Stroke, 2013. 44(11): p. 3129-35.
  290. Khor, M.X., et al., Pre-hospital notification is associated with improved stroke thrombolysis timing. J R Coll Physicians Edinb, 2015. 45(3): p. 190-5.
  291. van Wijngaarden, J.D., et al., Do centres with well-developed protocols, training and infrastructure have higher rates of thrombolysis for acute ischaemic stroke? Qjm, 2011. 104(9): p. 785-91.
  292. Joux, J., et al., Prehospital transfer medicalization increases thrombolysis rate in acute ischemic stroke. A French stroke unit experience. Clin Neurol Neurosurg, 2013. 115(9): p. 1583-5.
  293. Lahr, M.M., et al., The chain of care enabling tPA treatment in acute ischemic stroke: a comprehensive review of organisational models. J Neurol, 2013. 260(4): p. 960-8.
  294. Royal College of Physicians, Sentinel Stroke National Audit Programme (SSNAP) Clinical audit August-November 2016 Public Report National Results. 2017, Royal College of Physicians: London.
  295. Crichton, S.L., et al., Patient outcomes up to 15 years after stroke: survival, disability, quality of life, cognition and mental health. Journal of Neurology, Neurosurgery & Psychiatry, 2016. 87(10): p. 1091-1098.
  296. Gallacher, K.I., et al., Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden. BMC Medicine, 2014. 12(1): p. 151.
  297. Horgan, F., et al., Irish National Audit of Stroke Care. 2008, Dublin: Irish Heart Foundation.
  298. Groeneveld, I.F., et al., Practice Variation in the Structure of Stroke Rehabilitation in Four Rehabilitation Centres in the Netherlands. Journal of rehabilitation medicine, 2016. 48(3): p. 287-292.
  299. Wiedmann, S., et al., Variations in quality indicators of acute stroke care in 6 European countries: the European Implementation Score (EIS) Collaboration. Stroke, 2012. 43(2): p. 458-63.
  300. European Stroke Organisation Executive Committee, Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. Cerebrovascular diseases, 2008. 25(5): p. 457-507.
  301. Pollock, A., et al., Physical rehabilitation approaches for the recovery of function and mobility following stroke. Cochrane Database Syst Rev, 2014. 4: p. Cd001920.
  302. Lejeune, T., Early discharge after stroke: A Belgian experience, in 19th European Congress of Physical and Rehabilitation Medicine. 2014: Marseille.
  303. Lains, J. Early post-stroke rehabilitation in Portugal. in Annals of Physical and Rehabilitation Medicine. 2014.
  304. Dimova, A., et al., Bulgaria: Health system review, in Health Systems in Transition. 2012, European observatory on health systems and policies.
  305. Milicic, D., Country report Croatia – December 2015, in Country of the Month, E.S.o. Cardiology, Editor. 2015.
  306. Theodorou, M., et al., Cyprus: Health system review, in Health Systems in Transition. 2012, European observatory on health systems and policies.
  307. McGee, H., Changing Cardiovascular Health: National Cardiovascular Health Policy 2010-2019, D.O.H.A. CHILDREN, Editor. 2010: Ireland.
  308. Szczerbińska, K., et al., Trajectory of care for an elderly stroke patient in the new EU member countries–based on CLESA project. European Geriatric Medicine, 2010. 1(1): p. 32-40.
  309. Asplund, K., et al., Diagnostic procedures, treatments, and outcomes in stroke patients admitted to different types of hospitals. Stroke, 2015. 46(3): p. 806-12.
  310. Koskinen, M., CVA rehabilitation 2013-15 final report [AVH:n sairastaneiden kuntoutukseen ohjautuminen ja kuntoutuksen toteutuminen 2013–2015: AVH-kuntoutuksen seurantatutkimuksen loppuraportti]. 2016, Aivoliitto: Turku.
  311. Opara, J.A., et al., Facilities of early rehabilitation after stroke in Poland 2010. Int J Rehabil Res, 2012. 35(4): p. 367-71.
  312. ESRI and RCSI, Towards Earlier Discharge, Better Outcomes, Lower Cost: Stroke Rehabilitation in Ireland. 2014.
  313. De Wit, L., et al., Use of time by stroke patients a comparison of four European rehabilitation centers. Stroke, 2005. 36(9): p. 1977-1983.
  314. Otterman, N.M., et al., Physical therapists’ guideline adherence on early mobilization and intensity of practice at dutch acute stroke units: a country-wide survey. Stroke, 2012. 43(9): p. 2395-401.
  315. Royal College of Physicians, How good is stroke care? First SSNAP Annual Report April 2013 to March 2014. 2014, Royal College of Physicians: London.
  316. Fearon, P. and P. Langhorne, Services for reducing duration of hospital care for acute stroke patients. Cochrane Database Syst Rev, 2012(9): p. Cd000443.
  317. Saka, O., A. McGuire, and C. Wolfe, Cost of stroke in the United Kingdom, in Age Ageing. 2009: England. p. 27-32.
  318. Nordin, Å., K.S. Sunnerhagen, and Å.B. Axelsson, Patients’ expectations of coming home with Very Early Supported Discharge and home rehabilitation after stroke – an interview study. BMC Neurology, 2015. 15: p. 235.
  319. Department of Health, National Stroke Strategy, D.o. Health, Editor. 2007, Department of Health: London.
  320. National Institute for Health and Care Excellence, Stroke rehabilitation in adults Clinical guideline [CG162]. 2013, NICE: London.
  321. Royal College of Physicians, Sentinel Stroke National Audit Programme (SSNAP) Acute organisational audit report November 2016. 2016, Royal College of Physicians: London.
  322. Royal College of Physicians, National clinical guideline for stroke: Fifth edition. 2016, Royal College of Physicians: London.
  323. Royal College of Physicians, Sentinel Stroke National Audit Programme (SSNAP) Clinical audit April-July 2016 Public Report National results. 2016, Royal College of Physicians: London.
  324. Bodechtel, U., et al., The stroke east Saxony pilot project for organised post-stroke care: a case–control study. Brain and Behavior, 2016. 6(5): p. e00455-n/a.
  325. Townsley, R., et al., The Implementation of Policies Supporting Independent Living for Disabled People in Europe: Synthesis Report, A.N.o.E.D.e. (ANED), Editor. 2010: Bristol.
  326. Santana, S., et al., Early home-supported discharge for patients with stroke in Portugal: A randomised controlled trial. Clin Rehabil, 2016.
  327. Socialstyrelsen, National Performance Assessment 2011 – Quality and Efficiency of Stroke Care in Sweden. 2011. p. 86.
  328. Hauben, H., et al., Assessing the impact of European governments’ austerity plans on the rights of people with disabilities. Bernard Brunhes International, 2012.
  329. Pasternack, I., et al., Who Should Receive Vocationally Oriented Multidisciplinary Intervention for Work Ability?, in Health Technology Assessment International 2014. 2014: Washington DC.
  330. Dorning H, et al., Knowing you’re not alone: Understanding peer support for stroke survivors. 2016, Nuffield Trust.
  331. Neeman Association for Stroke Survivors, Life after a stroke: guidance booklet for the injured and their families. 2014.
  332. Arboix, A., et al., Trends in risk factors, stroke subtypes and outcome. Nineteen-year data from the Sagrat Cor Hospital of Barcelona stroke registry. Cerebrovasc Dis, 2008. 26(5): p. 509-16.
  333. Vemmos, K.N., et al., Prognosis of stroke in the south of Greece: 1 year mortality, functional outcome and its determinants: the Arcadia Stroke Registry. J Neurol Neurosurg Psychiatry, 2000. 69(5): p. 595-600.
  334. Vilionskis A., D. Jatužis, and V. Budrys, Intravenous thrombustaikymas kliniineje everyday practice Vilnius city and district in patients with acute ischemic stroke. 2013: Neurologijos Seminarai. p. 150-154.
  335. Mallia, M., et al., Benchmarking local practice in view of introduction of thrombolysis for stroke in Malta. Malta Medical Journal, 2015. 27(01).
  336. Papapanagiotou, P., et al., Temporal trends and associated factors for pre-hospital and in-hospital delays of stroke patients over a 16-year period: the Athens study. Cerebrovasc Dis, 2011. 31(2): p. 199-206.
  337. Gattringer, T., et al., Sex-related differences of acute stroke unit care: results from the Austrian stroke unit registry. Stroke, 2014. 45(6): p. 1632-8.
  338. Demant, M.N., et al., Temporal trends in stroke admissions in Denmark 1997-2009. BMC Neurol, 2013. 13: p. 156.
  339. Guize, L., et al., [Atrial fibrillation: prevalence, risk factors and mortality in a large French population with 15 years of follow-up]. Bull Acad Natl Med, 2007. 191(4-5): p. 791-803; discussion 803-5.
  340. Charlemagne, A., et al., Epidemiology of atrial fibrillation in France: extrapolation of international epidemiological data to France and analysis of French hospitalization data, in Arch Cardiovasc Dis. 2011, 2011 Elsevier Masson SAS: Netherlands. p. 115-24.
  341. Samol, A., et al., Prevalence of unknown atrial fibrillation in patients with risk factors. Europace, 2013. 15(5): p. 657-62.
  342. Schmidt, M., et al., 30-year nationwide trends in incidence of atrial fibrillation in Denmark and associated 5-year risk of heart failure, stroke, and death. Int J Cardiol, 2016. 225: p. 30-36.
  343. Gomes, E., et al., [FATA Study: prevalence of atrial fibrillation and antithrombotic therapy in primary health care in a northern city of Portugal]. Acta Med Port, 2015. 28(1): p. 35-43.
  344. Perez-Villacastin, J., N. Perez Castellano, and J. Moreno Planas, Epidemiology of atrial fibrillation in Spain in the past 20 years, in Rev Esp Cardiol (Engl Ed). 2013, 2013 Sociedad Espanola de Cardiologia. Published by Elsevier Espana: Spain. p. 561-5.
  345. Baena-Diez, J.M., et al., Prevalence of atrial fibrillation and its associated factors in Spain: An analysis of 6 population-based studies. DARIOS Study. Rev Clin Esp, 2014. 214(9): p. 505-12.
  346. Bjorck, S., et al., Atrial fibrillation, stroke risk, and warfarin therapy revisited: a population-based study. Stroke, 2013. 44(11): p. 3103-8.
  347. SITS International Coordination Team, SITS Report 2016. 2016, SITS: Stockholm.
  348. Charalampous, M., Personal communication, KCL, Editor. 2016.
  349. Guidetti, D., et al., Post-stroke rehabilitation in Italy: inconsistencies across regional strategies, in Eur J Phys Rehabil Med. 2014: Italy. p. 335-41.
  350. Berzina, G., A. Vetra, and K.S. Sunnerhagen, A comparison of stroke rehabilitation; data from two national cohorts. Acta Neurol Scand, 2015.
  351. Heijnen, R., et al., Towards a better integrated stroke care: the development of integrated stroke care in the southern part of the Netherlands during the last 15 years (Special 10th Anniversary Edition paper). International Journal of Integrated Care, 2012. 12: p. e123.
  352. Ullberg, T., et al., Doctor’s follow-up after stroke in the south of Sweden: An observational study from the Swedish stroke register (Riksstroke). European Stroke Journal, 2016. 1(2): p. 114-121.
  353. Royal College of Physicians. Welcome to SSNAP (Homepage). 2016 [cited 2017 23/01/2017]; Available from: https://www.strokeaudit.org/Home.aspx.
  354. Jauch, E.C., et al., Guidelines for the early management of patients with acute ischemic stroke. Stroke, 2013. 44(3): p. 870-947.
  355. Wiedmann, S., et al., Variations in acute hospital stroke care and factors influencing adherence to quality indicators in 6 European audits. Stroke, 2015. 46(2): p. 579-81.